KEGG   Homo sapiens (human): 5501
Entry
5501              CDS       T01001                                 
Symbol
PPP1CC, PP-1G, PP1C, PPP1G
Name
(RefSeq) protein phosphatase 1 catalytic subunit gamma
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04390  Hippo signaling pathway
hsa04510  Focal adhesion
hsa04611  Platelet activation
hsa04720  Long-term potentiation
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04810  Regulation of actin cytoskeleton
hsa04910  Insulin signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04931  Insulin resistance
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05168  Herpes simplex virus 1 infection
hsa05205  Proteoglycans in cancer
hsa05415  Diabetic cardiomyopathy
Network
nt06168  Herpes simplex virus 1 (HSV-1)
nt06515  Regulation of kinetochore-microtubule interactions
nt06526  MAPK signaling
  Element
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
N01531  CENPE interaction with NDC80 complex
N01536  Dephosphorylation of kinetochore
N01598  Regulation of GF-RTK-RAS-ERK signaling, MRAS-SHOC2-PP1 holophosphatase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5501 (PPP1CC)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5501 (PPP1CC)
   04024 cAMP signaling pathway
    5501 (PPP1CC)
   04022 cGMP-PKG signaling pathway
    5501 (PPP1CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5501 (PPP1CC)
   04218 Cellular senescence
    5501 (PPP1CC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5501 (PPP1CC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    5501 (PPP1CC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5501 (PPP1CC)
  09152 Endocrine system
   04910 Insulin signaling pathway
    5501 (PPP1CC)
   04921 Oxytocin signaling pathway
    5501 (PPP1CC)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5501 (PPP1CC)
   04270 Vascular smooth muscle contraction
    5501 (PPP1CC)
  09156 Nervous system
   04728 Dopaminergic synapse
    5501 (PPP1CC)
   04720 Long-term potentiation
    5501 (PPP1CC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5501 (PPP1CC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5501 (PPP1CC)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    5501 (PPP1CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    5501 (PPP1CC)
   05034 Alcoholism
    5501 (PPP1CC)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    5501 (PPP1CC)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    5501 (PPP1CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5501 (PPP1CC)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5501 (PPP1CC)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5501 (PPP1CC)
   03041 Spliceosome [BR:hsa03041]
    5501 (PPP1CC)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5501 (PPP1CC)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     5501 (PPP1CC)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     5501 (PPP1CC)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     5501 (PPP1CC)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    5501 (PPP1CC)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 5501
NCBI-ProteinID: NP_002701
OMIM: 176914
HGNC: 9283
Ensembl: ENSG00000186298
UniProt: P36873
Structure
Position
12:complement(110708376..110742891)
AA seq 323 aa
MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
KKKPNATRPVTPPRGMITKQAKK
NT seq 972 nt   +upstreamnt  +downstreamnt
atggcggatttagataaactcaacatcgacagcattatccaacggctgctggaagtgaga
gggtccaagcctggtaagaatgtccagcttcaggagaatgaaatcagaggactgtgctta
aagtctcgtgaaatctttctcagtcagcctatcctactagaacttgaagcaccactcaaa
atatgtggtgacatccatggacaatactatgatttgctgcgactttttgagtacggtggt
ttcccaccagaaagcaactacctgtttcttggggactatgtggacaggggaaagcagtca
ttggagacgatctgcctcttactggcctacaaaataaaatatcctgagaatttttttctt
ctcagagggaaccatgaatgtgccagcatcaacagaatttatggattttatgatgaatgt
aaaagaagatacaacattaaactatggaaaactttcacagactgttttaactgtttaccg
atagcagccatcgtggatgagaagatattctgctgtcatggaggtttatcaccagatctt
caatctatggagcagattcggcgaattatgcgaccaactgatgtaccagatcaaggtctt
ctttgtgatcttttgtggtctgaccccgataaagatgtcttaggctggggtgaaaatgac
agaggagtgtccttcacatttggtgcagaagtggttgcaaaatttctccataagcatgat
ttggatcttatatgtagagcccatcaggtggttgaagatggatatgaattttttgcaaag
aggcagttggtcactctgttttctgcgcccaattattgcggagagtttgacaatgcaggt
gccatgatgagtgtggatgaaacactaatgtgttcttttcagattttaaagcctgcagag
aaaaagaagccaaatgccacgagacctgtaacgcctccaaggggtatgatcacaaagcaa
gcaaagaaatag

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